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FirstPrinciples

FirstPrinciples is building AI to accelerate scientific discovery.

3 open roles3 remote

Open roles at FirstPrinciples

3 positions we're tracking, re-checked daily

Working at FirstPrinciples

FirstPrinciples is building AI to accelerate scientific discovery.

3 of the 3 open roles are remote.

How to actually get hired at FirstPrinciples

Why applying the normal way doesn't work

FirstPrinciples runs an applicant tracking system (Ashby), but hiring managers still work referrals first. A cold application to FirstPrinciples isn't dead, it's just fourth in line behind internal referrals, sourced candidates and recruiter pipelines.

Who to contact at FirstPrinciples

We haven't verified a contact route at FirstPrinciples yet. The decision usually sits with the hiring manager for the team that's hiring, but that's a model, not something we've confirmed. Members get verified contacts first.

What FirstPrinciples screens for

relevant experience and ability to operate autonomously

Tailor your CV to the specific FirstPrinciples role rather than sending a general one. Applications that mirror the language of the job description clear automated filters at a materially higher rate.

Mistakes that kill FirstPrinciples applications

  • Don't send the same CV you sent everywhere else. Whoever reads applications at FirstPrinciples can tell, and it's the fastest rejection there is.

  • Lead with their problem, not your ambition. FirstPrinciples is focused on is growing — show you understand that.

  • Applying and waiting = silence. Follow up at day five — it roughly doubles your odds of a reply.

Tracking FirstPrinciples

Applying to FirstPrinciples? Get the contact, not the form.

Free to try: see the roles that fit you and who's hiring for them. No sign-up to start.

FirstPrinciples careers: frequently asked questions

How many jobs does FirstPrinciples have open?

We're tracking 3 active openings at FirstPrinciples (verified November 4, 2026).

Does FirstPrinciples hire remotely?

Yes, 3 of the 3 current FirstPrinciples vacancies are remote.

What roles is FirstPrinciples hiring for?

FirstPrinciples is hiring for roles including Account Executive, Technical Account Executive and Growth Marketing Manager. The most recent opening is Account Executive.

How do I apply for a job at FirstPrinciples?

Click through to apply, or see our detailed guide on landing a job at FirstPrinciples.

Does FirstPrinciples respond to cold emails?

We haven't verified response rates at FirstPrinciples yet.

Who is the hiring manager at FirstPrinciples?

We haven't confirmed who leads hiring at FirstPrinciples. It's usually the manager of the team that's hiring.

What ATS does FirstPrinciples use?

FirstPrinciples uses Ashby.

How competitive is it to get hired at FirstPrinciples?

A role at FirstPrinciples typically draws 100-250 applicants in the first two weeks. Applying inside 72 hours of a posting going live is the single biggest lever you control.

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