Senior Software Engineer, Product

About Boltz

Boltz is a public benefit company building the next generation of AI-powered molecular modeling tools to make biology programmable and accelerate drug discovery, while keeping frontier capabilities broadly accessible.

Boltz began as an MIT spin-out. Our founders built Boltz-1 at MIT, and it became the first fully open-source model to match AlphaFold 3's accuracy in predicting the 3D structure of biomolecular complexes.

We focus on two things

• Open foundation models. Boltz-1, Boltz-2, and BoltzGen are open models trusted by 100,000+ scientists across biotech and academia, and used in programs at every Top 20 pharma as well as leading agrichemical and industrial research organizations.
• Boltz Lab. Our commercial platform runs our latest models and design agents as reliable, production-grade tools built around real chemistry and biology workflows. Teams start from a target and a hypothesis, then generate, evaluate, and rank candidate molecules, while we provide the compute, infrastructure, and collaboration layer so their scientists can move faster.

The two feed each other: open-source adoption earns scientific credibility and community insight, and Boltz Lab turns that into real impact on our partners' discovery programs.

You can read more about our mission, research and product vision in our manifesto.

About the role

As a Software Engineer on Product, you will own the parts of Boltz Lab that scientists see and use every day, turning advanced ML and molecular modeling into clear, usable workflows. Boltz Lab is how our models reach partners' discovery programs, so the product experience decides how much value they get from them.

You will work closely with our Product Designer, ML Research and domain scientists to shape the end-to-end experience, from interface to API.

This role is ideal for someone who cares about usability and clarity, and enjoys turning complex technical systems into elegant products that people rely on daily.

What you'll do

• Design and ship Boltz Lab features end to end, from front-end interfaces to the APIs and application logic behind them.
• Build interactive workflows that help scientists explore results, compare candidates and iterate on designs.
• Make model outputs understandable and trustworthy, working with design and research on how results are presented.
• Keep the product codebase clean, tested and maintainable as it grows.
• Watch how scientists use the product, and feed what you learn back into the roadmap and our models' outputs.

About you

Minimum Requirements

• 6+ years of strong experience building and shipping user-facing products in production.
• Full-stack web development with modern frameworks and languages (e.g. TypeScript, React, Python), including the APIs behind your UI.
• Solid engineering fundamentals: clean abstractions, maintainability and testing.
• A track record of owning features end to end, from design through launch, iteration and maintenance.
• Close collaboration with designers, product partners and researchers to turn user needs into thoughtful technical solutions.

Preferred Requirements

• Exposure to computational biology, chemistry or other scientific domains, or ML-powered products that expose model outputs to users.
• Early-stage startup experience, or building tools for technical users (developer platforms, data tools, research software).
• Experience using Boltz models, or open-source contributions.

We know great people don't always tick every box. If this role excites you and you meet most of the minimum requirements, we'd like to hear from you.

What we offer

• Ownership of the product scientists at leading discovery teams use to design new medicines.
• Work alongside one of the most talent-dense teams in the field.
• Significant ownership and independence, with responsibility for driving projects from concept to deployment.
• Highly competitive salary with meaningful equity in a public benefit company.
• Benefits:
• 25 days annual leave plus bank holidays
• Annual team offsite trip
• Private healthcare (BUPA), covering pre-existing conditions
• Pension program
• Paid parental leave
• Wellhub gym membership
• Free lunch every day
• Travel expenses

How we hire

1. Initial screen with a member of the Talent team
2. Technical interview
3. Onsite in London or virtual onsite with the team
4. Offer + Onboarding

Our commitment

Boltz is committed to building a diverse team and an inclusive workplace. We welcome applicants of all backgrounds. If you need any adjustments during the hiring process, tell us and we'll make it work.